David J. Dooley, Ph.D.

CAREER SUMMARY

An expert neuropharmacologist, accomplished drug hunter with in-depth knowledge and broad expertise gained from 27 years in major pharmaceutical companies. He has extensive knowledge of neurological and psychiatric disorders with a talent to lead and mentor scientists and project teams. His proven ability to generate and advance novel ideas to testing in the laboratory setting has contributed to the nomination of 12 clinical candidates, 6 being advanced to clinical testing.

KEY ACCOMPLISHMENTS

Preclinical CNS Research

  • Extensive experience of preclinical basic and applied CNS drug discovery research at several international pharmaceutical firms
  • Led a staff of associate scientists, post-doctoral researchers, and student interns in an in vitro neuropharmacology laboratory setting to identify compounds for further develop-ment as potential drugs and to establish new assays enhancing drug discovery efforts
Project Management
  • Served as team leader and member of multidisciplinary team liaising with biologists, chemists, toxicologists, clinicians, and managers on drug discovery projects effectively advancing several drug candidates to extensive preclinical evaluation as a prerequisite to clinical development for multiple indications
External Visibility
  • Initiated and maintained several international academic collaborations enhancing drug discovery and basic research efforts as development opportunities to progress the science
  • Published more than 50 papers in peer-reviewed journals, and presented at more than 70 international scientific meetings
  • Senior-authored a key opinion article (Trends Pharmacol. Sci. 28 (2007) 75-82) on the mechanism of action of the novel, Pfizer-marketed drugs gabapentin (Neurontin®) and pregabalin (Lyrica®)
  • Initiated research or developed conceptions resulting in ten issued patents

EDUCATION

Ph.D. - Neuropharmacology, University of Washington, Seattle, WA 1979
M.A. - Psychopharmacology, Humboldt State University, Arcata, CA 1974
B.A. - Physiological Psychology, Humboldt State University, Arcata, CA 1972